Friday, March 17, 2006

Not Mercury on Glutathione: What is it and why should we care?

Not Mercury: Glutathione: What is it and why should we care?

Not Mercury:
Technically these aren't two distinct forms but rather two oxidation states of the same molecule with a clear inverse relationship. When levels of one drop and the other increases. Not what we would want to call a "severe deficit" but possibly suggestive of a pro-oxidative environment.

If you are going to understand glutathione you need to know that redox reactions (reduction/oxygenation) occur when a some molecules pass ions (electrons) back and forth. When the extra negative ion is on one molecule that molecule is "reduced", that is its "charge" is reduced because it has a negatively charged ion attached to it (that ion is symbolized by a minus sign (-), if you see that which helps to understand that you are adding more negativity when you add negative ion). The molecule that is donating that negative ion loses that negative charge and is said to be "oxidized," even when oxygen isn't involved. How's that for confusing?

And if that isn't bad enough, Not Mercury points out that there are two forms of glutathione--reduced glutathione and oxidized glutathione--and that the term "reduced" here sounds like, "less glutathione" or "low glutathione level", but "reduced" in this case is describing it's electrical charge.

The following is probably Autism Diva's favorite point made in this review of glutathione in autism:
If the average human carries around approximately 6 milligrams of mercury how much glutathione should we require to deal with environmental mercury levels ? Even if several molecules of glutathione were required for each mercury molecule, we should have millions of times sufficient glutathione to get the job done. Compare that to the reported upper limit of exposure through vaccines which has been estimated at less than 250 micrograms. A person so severely deficient in glutathione they would be unable to detoxify 250 micrograms of mercury probably wouldn't survive long enough to be vaccinated in the first place. Every breath of air would expose them to lethal levels of ozone, pollutants and other oxidants.


Oh, so autistic kids, in fact not any kids can live if they are chronically "on empty" when in comes to glutathione. All the mercury parents seem to like to quote Dr. Jill James and say that autistic kids have almost no glutathione and they all say that glutathione is what allows one to detoxify mercury and other heavy metals. All this misrepresentation of glutathione is more reason to distrust the sloppy, junk science producing,
2


armchair,
politicized,
paid "expert" witness,
and agenda laden
scientists who are constantly quoted by the mercury parents. Both Jill James (who's work with glutathione is oft quoted by the mercury parents) and Mady Hornig are mercury moms of autistic kids. Both seem to Autism Diva to work at keeping their autistic children in the closet. Autism Diva isn't saying that the children in question are literally kept in a closet, but that the parents keep their status as mercury parents in the closet. Jim Adams, the materials scientist cum autism dietician and chelation investigator, of Arizona State University (edit: Autism Diva had written that Adams was with the University of Arizona, which is wrong), is likewise a mercury dad, though his status as a parent is not hidden.

But, back to Not Mercury and his great blog entry on glutathione... please go read it on the Not Mercury blog here.



Autism Diva
measurable

1 Comments:

Blogger Ed in Colorado said...

It is interesting to note that low levels of reduced glutathione are found in autism, alzheimers, parkinsons, dialysis dementia, alcoholics dementia and downs syndrome. Also of interest is that when people have a genetic defect where they lose the ability to manufacture glutathione at the body's normal rate, they suffer brain abnormalities. Also interesting, mercury lowers the level of glutathione in the body.

12:01 AM  

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